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Prescription Only

Skinoren 20% Cream

Skinoren is a prescription-strength cream used to treat acne and rosacea.

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£19.99£29.99

Price varies by strength. Includes prescription review.

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Reviewed by UK-registered prescribers
Discreet next-day delivery
Ongoing clinical support included
GPhC-registered pharmacy

Description

Skinoren is a topical prescription cream containing azelaic acid 20%, a dicarboxylic acid with antibacterial, anti-inflammatory, and comedolytic properties. It works by attacking the root causes of acne and rosacea: excess skin cell production, blocked pores, and bacterial overgrowth. Azelaic acid inhibits the growth of Propionibacterium acnes, the bacteria that contributes to acne inflammation, and helps regulate the production of keratin—a protein that can block pores. For rosacea, Skinoren helps reduce inflammatory lesions and persistent redness by soothing vascular inflammation and limiting reactive oxygen species that trigger skin irritation. It also has a mild skin-lightening effect, which can improve post-acne pigmentation and uneven tone over time.

Why Choose Skinoren

Skinoren is clinically proven to improve the appearance of acne and rosacea with continued use. Its dual-action formula makes it one of the few treatments prescribed for both conditions, offering a versatile option for patients who suffer from inflammatory skin issues. Skinoren is non-antibiotic, meaning it can be used long-term without risk of bacterial resistance. It is non-comedogenic, free from fragrances and unnecessary irritants, and generally well tolerated by most skin types. Many users notice a reduction in breakouts, redness, and post-inflammatory pigmentation within 4 to 8 weeks. Its suitability for daily use under medical supervision makes it a reliable option in both standalone and combination skincare regimens.

Important Note

Skinoren is for external use only and should be applied as a thin layer over the entire affected area—not as a spot treatment. It should not be used on broken or inflamed skin unless advised by a prescriber. Temporary skin irritation, such as itching or mild burning, may occur in the first week of use; this often resolves with continued use. If symptoms persist or worsen, reduce application frequency or consult your healthcare provider. Avoid contact with the eyes, mouth, and inside of the nose. Do not use Skinoren during pregnancy or breastfeeding unless advised by a healthcare professional.

Directions

Please refer to the medication’s patient information leaflet before starting any new medication.

  • Apply a thin layer of Skinoren to the affected areas twice daily—morning and evening.

  • Use on clean, dry skin and massage gently until fully absorbed.

  • Wash hands after application.

  • Avoid applying to broken skin or near the eyes and mouth.

If irritation occurs, reduce use to once daily and consult a healthcare provider if symptoms persist.

Store below 25°C. Keep in the original packaging and out of reach of children.

Ingredients

Active Ingredient:

  • Azelaic acid 20% w/w

Other Ingredients:

  • Benzoic acid

  • Glycerol

  • Cetostearyl alcohol

  • Propylene glycol

  • Purified water

Side Effects

Common side effects may include:

  • Burning or stinging sensation

  • Dryness

  • Itching

  • Skin peeling

  • Redness

Serious (rare) side effects:

  • Severe skin irritation

  • Allergic skin reaction

  • Swelling or blistering

  • Shortness of breath (if misused or ingested)

Stop the medicine and seek medical attention if serious side effects occur.

Warnings

  • Allergies: Do not use Skinoren if allergic to azelaic acid or any other ingredients in the formula.

  • Pregnancy and Breastfeeding: Use only if prescribed and approved by a healthcare provider.

  • Medical Conditions: Not recommended for use on broken or sunburned skin. Avoid if you have hypersensitive skin disorders unless advised.

  • Age Restrictions: Not suitable for children unless prescribed.

  • Drug Interactions: Avoid use with harsh skincare agents or alcohol-based products that may increase irritation.

How It Works

Treatment in five simple steps

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1

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2

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3

Clinical review

A qualified clinician checks it's safe and right for you. You'll be refunded if it's not right for you.

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4

Pharmacist check

Our pharmacist does a final check before your medicine is dispensed.

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5

Delivered to your door

Your order arrives in plain, unbranded packaging, with next day delivery available.

Patient Reviews

What our patients say

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Best pharmacy service I've used. Properly supported with check-ins — not just a dispensing machine. Real clinical care.

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I was nervous about ordering online but the team were so professional and the consultation felt thorough. Highly recommend.

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Incredibly smooth process from start to finish. Medication arrived the next day in discreet packaging. Will definitely use again.

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