GPhC Registered Pharmacy — Verified & Trusted
Prescription Only
Out of stock

Esomeprazole GR 20mg

Esomeprazole is a PPI treatment for acid reflux, heartburn, and ulcers, offering powerful acid suppression with once-daily convenience.Packaging and branding may differ from image shown.

Starting from
£22.49

Price varies by strength. Includes prescription review.

Order within 0h 0m for next day delivery on all items
Reviewed by UK-registered prescribers
Discreet next-day delivery
Ongoing clinical support included
GPhC-registered pharmacy

Description

Esomeprazole is a proton pump inhibitor (PPI) used for managing acid-related gastrointestinal conditions. It is particularly effective in treating gastro-oesophageal reflux disease (GORD), peptic ulcers, and Zollinger-Ellison syndrome. Esomeprazole provides symptom relief and promotes healing in acid-damaged tissues. It is often prescribed as a longer-term solution when other acid suppressants are not sufficient.

How It Works
Esomeprazole blocks the proton pump in the stomach lining, which is the final pathway for acid secretion. This action significantly reduces gastric acid production, lowering the acidity of the stomach contents. By reducing acid exposure, Esomeprazole relieves symptoms like heartburn, aids the healing of ulcers, and helps prevent acid-related damage to the oesophagus. Its long-lasting effect allows for once-daily dosing in most cases, though more severe cases may require higher doses or twice-daily administration.

Why Choose Esomeprazole
Esomeprazole is considered one of the most effective PPIs available. It offers strong acid suppression, with better bioavailability than some other agents in its class, especially in maintaining stable blood levels. Patients with moderate to severe reflux symptoms or those who do not respond adequately to other PPIs often benefit from switching to Esomeprazole. Its once-daily formulation helps improve adherence and allows consistent control of symptoms.

Important Note
Esomeprazole should only be used under medical guidance. Long-term use may be associated with a risk of vitamin B12 deficiency, magnesium imbalance, or bone fracture. It may also interact with medications such as clopidogrel, warfarin, or antifungals. Patients should not stop or change their dose without consulting a doctor. If symptoms persist despite treatment, further evaluation may be required to rule out more serious gastrointestinal conditions.

Directions

Please refer to the medication’s patient information leaflet before starting any new medication.

  • Take once daily, at least one hour before a meal

  • Swallow whole with water

  • Do not chew or crush the tablets or capsules

  • Follow the prescribed course duration

  • Store below 25°C

  • Keep in original packaging

  • Keep out of reach of children

Ingredients

Active Ingredient:

  • Esomeprazole magnesium 20 mg or 40 mg

Other Ingredients:

  • Magnesium stearate

  • Cellulose compounds

  • Hypromellose

  • Macrogol

  • Titanium dioxide

  • Gelatin (for capsules)

Side Effects

Common side effects may include:

  • Headache

  • Diarrhoea or constipation

  • Stomach pain

  • Nausea

Serious (rare) side effects:

  • Low magnesium levels

  • Severe allergic reaction

  • Fractures (with long-term use)

  • Clostridium difficile-associated diarrhoea

Stop the medicine and seek medical attention if serious side effects occur.

Warnings

Do not use Esomeprazole if allergic to any PPIs or other ingredients in the formulation. Long-term use should be monitored, especially in older adults or patients with osteoporosis, liver impairment, or those taking interacting medications. Consult your doctor if pregnant, planning pregnancy, or breastfeeding.

How It Works

Treatment in five simple steps

No GP appointment needed. Here's what happens.

1

Start consultation

Answer a few questions about your health. It only takes a few minutes.

→
2

Choose a treatment

Choose the option you'd like and check out.

→
3

Clinical review

A qualified clinician checks it's safe and right for you. You'll be refunded if it's not right for you.

→
4

Pharmacist check

Our pharmacist does a final check before your medicine is dispensed.

→
5

Delivered to your door

Your order arrives in plain, unbranded packaging, with next day delivery available.

Patient Reviews

What our patients say

Real feedback from real patients.

“

Best pharmacy service I've used. Properly supported with check-ins — not just a dispensing machine. Real clinical care.

MS
Mitesh S.Verified Patient
“

I was nervous about ordering online but the team were so professional and the consultation felt thorough. Highly recommend.

NH
Nicola H.Verified Patient
“

Incredibly smooth process from start to finish. Medication arrived the next day in discreet packaging. Will definitely use again.

GE
Gareth E.Verified Patient

Patient stories

Hear from patients about their experience, in their own words.

Who Are We

A pharmacy team you can trust

We’re a GPhC registered pharmacy run by qualified pharmacists and clinicians. Every consultation is reviewed by a real person, because your health deserves more than a tick box.

Clinically governed Every order reviewed by a qualified clinician before dispensing.
Patient-first approach We treat patients, not orders. Clinical support throughout your treatment.
Transparent & compliant Fully compliant with GPhC, MHRA, and NHS standards.
Learn More About Us
Patient Support Customer Care
Pharmacist 2
Clinical Lead
Dispenser

Ready to get started?

Start your consultation online or speak to our pharmacy team. We're here to help.

Trusted By & Working With